Ho bile le thahasello e ntseng e hola molemong oa bophelo bo botle le melemo ea nako e telele ea tlatsetso ea NMN (Nicotinamide Mononucleotide) lilemong tsa morao tjena. Joaloka motho ea khahliloe haholo ke ntlha ea ho qetela ea saense le bophelo bo botle, ke ile ka tloha leetong la ho batlisisa taba ena ho ea pele. Ke batla ho fana ka leseli mabapi le mekhoa ea tlatsetso ea NMN le litlamorao tsa eona bakeng sa bophelo bo botle ba motho le bophelo bo bolelele ka lipatlisiso le tlhahlobo e hlokolosi.
Ho Fuputsa Mahlale ka morao ho NMN
Mekhoa ea mahlale e tšehetsang tlatsetso ea NMN (Nicotinamide Mononucleotide) e bohlokoa bakeng sa ho utloisisa katleho ea eona. NMN ke selelekela se tobileng sa nicotinamide adenine dinucleotide (NAD +), coenzyme ea bohlokoa e amehang ho metabolism ea matla, tokiso ea DNA, le taolo ea polelo ea liphatsa tsa lefutso, tseo kaofela li leng bohlokoa bakeng sa bophelo bo botle. Tlatsetso ea NMN e na le monyetla oa ho fana ka melemo ea kalafo ho botsofali le mafu a amanang le lilemo ka ho phahamisa maemo a NAD+. Sena se na le ts'episo ea ho ntlafatsa ts'ebetso ea cellular, ho khothaletsa bophelo bo bolelele, le ho fokotsa ho theoha ho amanang le botsofali. "
Ho bula Khokahanyo lipakeng tsa NMN le Litsela tsa Bophelo bo Bolelele
Sirtuin pathway ke e 'ngoe ea litsela tsa mantlha tseo ka tsona Β-Nicotinamide Mononucleotidenmn e ama bophelo bo bolelele. Li-Sirtuin ke lelapa la NAD + -e itšetlehileng ka li-protein deacetylases tse laolang mekhoa e fapaneng ea likokoana-hloko tse bohlokoa bakeng sa ho fetola nako ea bophelo le ho thusa ho boloka homeostasis ea cellular. NMN Nicotinamide Mononucleotide Powder, ka ho thusa maemo a NAD+, ho ntlafatsa motsamao oa sirtuin, o baliloeng hohle bakeng sa bokhoni ba ona ba ho hola ka mokhoa o itekanetseng le ho holisa tebello ea bophelo. Mokhoa o ts'episang oa ho batlisisa mehato e reretsoeng ho khothaletsa botsofali bo botle le bophelo bo bolelele bo totobatsoa ke ts'ebetso ea li-sirtuin ke tlatsetso ea NMN.
Ho Lekola Tšusumetso ho Bophelo bo Botle ba Metabolic
Ho tlatselletsa le NMN (Nicotinamide Mononucleotide) ho hohetse tlhokomelo e ngata ka lebaka la Β-Nicotinamide Mononucleotidenmn litlamorao tse ka bang teng ho bophelo bo botle ba metabolic ho kenyelletsa karolo ea eona e tsebahalang ea ho lelefatsa bophelo. Lipatlisiso li fana ka maikutlo a hore NMN e ka eketsa kutloisiso ea insulin le ho ntlafatsa ts'ebetso ea mitochondrial, e leng karolo ea bohlokoa ea tlhahiso ea matla a cellular. Liphetho tsena li fana ka maikutlo a hore NMN e kanna ea thusa ba nang le maemo a metabolic ho kenyelletsa lefu la tsoekere la mofuta oa 2 le botenya.
Ka ho ntlafatsa mekhoa ea metabolic ka tšusumetso ea eona ts'ebetsong ea mitochondrial le kutloisiso ea insulin, NMN e na le ts'episo eseng feela ho lelefatsa nako ea bophelo empa hape le ho holiseng bophelo bo botle ba metabolic le matla. Lipatlisiso tse tsoelang pele mabapi le mekhoa ea NMN le bokhoni ba phekolo ea bophelo bo botle ba metabolic li ka senola mekhoa e mecha ea ho laola le ho thibela maloetse a metabolic."
Ho sebetsana le Senescence ea Cellular le Tšenyo ea DNA
Ho nka li-supplement tsa NMN (Nicotinamide Mononucleotide) ho bonahala e le mokhoa o motle oa ho loantša senescence ea lisele tse amanang le botsofali le tšenyo ea DNA. Ha lisele li ntse li tsofala, li bokella liphetoho tsa DNA 'me li bona ho bola, e leng ho eketsang mafu a amanang le batho ba hōlileng. Ka ho tšehetsa ho tsosolosoa ha lisele le ho ntlafatsa mekhoa ea ho lokisa DNA, NMN e bontša bokhoni ba ho fokotsa liphello tsena. Ka ho ntlafatsa bokhoni bo betere ba lisele, tlatsetso ea NMN e ka eketsa nako ea bophelo le ho sebetsa molemong oa ho bua ka bophelo bo botle ho batho ba ntseng ba hola."
Ho Hlahloba Bopaki bo Tsoang Lithutong Tsa Batho
Leha liphuputso tsa preclinical li bonts'itse litholoana tse ts'episang, ho bohlokoa ho hlahlobisisa bopaki bo tsoang litekong tsa batho ho utloisisa ka botlalo se boleloang ke tlatsetso ea NMN. Ho 'nile ha etsoa liteko tse' maloa tsa kliniki ho hlahloba tšireletseho le katleho ea NMN ho batho, ho senola liphuputso tsa pele tse fanang ka maikutlo a liphello tse ntle ho litekanyetso tsa metabolism, ts'ebetso ea 'mele, le bophelo bo botle ka kakaretso. Litlhaloso tsena li fana ka motheo oa bohlokoa oa ho tsoela pele ho hlahloba melemo le mefokolo ea NMN bophelong ba batho. "
Ho Utloisisa Bohlokoa ba Tekanyetso le Tsamaiso
Ho sebetsa ha NMN joalo ka tlatsetso ea lijo ho itšetlehile ka litekanyetso tse nepahetseng le mekhoa ea tsamaiso. Mekhoa e nepahetseng ea ho noa e ka fapana ho latela lintlha tse fapaneng joalo ka lilemo, boemo ba bophelo bo botle le boemo ba metabolism. Ka hona, ho bohlokoa hore batho ba nahanang ka tlatsetso ea NMN ba batle tataiso ho tsoa ho litsebi tsa bophelo bo botle. Ka kopanelo ho rala diprothokholo tsa motho ka mong ho netefatsa seo bongata ba nmn nicotinamide mononucleotide phofo e sebelisoa ka katleho ho sebetsana le litlhoko le lipakane tse khethehileng tsa bophelo bo botle, ho eketsa melemo ea eona e ka bang teng ha e ntse e netefatsa polokeho le katleho."
Ho Tsamaisa Boemo ba Litlatsetso tsa NMN
Ho hloka mohopolo o moholo ho tsamaisa lihlahisoa tsa NMN 'marakeng o ntseng o hola oa tlatsetso ea lijo. Ho bohlokoa ho etelletsa pele boleng le bohloeki. Ho etsa sena, khetha lihlahisoa tse tšepahalang tse latelang litataiso tse thata tsa tlhahiso le ho feta litekong tse ngata ho hlahloba litšila le matla. Melemo e meng e ka hlaha ka ho batlisisa ka lintho tsa synergistic, joalo ka quercetin le resveratrol, tse ka ntlafatsang ts'ebetso ea NMN. Ka ho etsa liqeto tse nang le tsebo e thehiloeng melaong ena, bareki ba ka ntlafatsa melemo ea bophelo bo botle ea tlatsetso ea NMN. "
Ho Amohela Mokhoa o Akaretsang oa Bophelo bo Bolelele
Leha tlatsetso ea NMN e bonts'a ts'episo ea ho khothaletsa bophelo bo botle le bophelo bo bolelele, mokhoa o akaretsang o kenyelletsang lintlha tse fapaneng tsa bophelo ke oa bohlokoa. Ho kenyelletsa boikoetliso ba kamehla, phepo e nepahetseng, taolo e sebetsang ea khatello ea maikutlo, le ho robala ka ho lekaneng ka synergistically ho tšehetsa bophelo bo botle ba lisele le bophelo bo bolelele. Ka ho kenyelletsa tlatsetso ea NMN molemong oa bophelo bo botle bo hlophisitsoeng ho latela litlhoko tsa motho ka mong, batho ba ka ntlafatsa bophelo ba bona le ho ntlafatsa boleng ba bophelo ba bona. Mokhoa ona o nang le likarolo tse ngata ha o sebetsane feela le lipakane tsa bophelo bo botle hang-hang empa hape o khothalletsa bophelo bo botle ba nako e telele, ho khothalletsa bophelo bo botle le bo khotsofatsang. "
fihlela qeto e
Ka kakaretso, Β-Nicotinamide Mononucleotidenmn tlatsetso e sebetsana le li-boondock tse hohelang sebakeng sa lipatlisiso tsa nako ea bophelo, e fanang ka liphihlelo tse khahlang likarolo tsa mafu a mantlha a ho hola le a amanang le lilemo. Ka litlamorao tse rarahaneng mabapi le bokhoni ba lisele, tšilo ea lijo, le ts'epo ea DNA, NMN e na le tiisetso e le sesebelisoa sa ho ntlafatsa bophelo bo botle le ho ntšetsa pele bohlokoa ho baahi ba ntseng ba hola. Leha ho le joalo, lipatlisiso tse eketsehileng lia hlokahala ho hlakisa litlamorao tsa eona tsa nako e telele le ho theha litataiso tse hlakileng tsa tšebeliso. Re ka kena leetong le lebisang bokamosong bo phetseng hantle le bo khotsofatsang haholoanyane ka ho nka mokhoa o potlakileng oa bophelo bo botle o kopanyang tlatsetso ea NMN le liphetoho tsa mokhoa oa bophelo ha re ntse re shebana le mathata a botsofali.
Haeba u na le lipotso kapa u thahasella lihlahisoa tsa rona, ka kopo ikopanye le rona: kiyo@xarbkj.com.
References
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