Ryonbio e tsepamisitse maikutlo ho hlahiseng lihlahisoa tsa limela, lihlahisoa tsa lihlahisoa tsa phepo e nepahetseng, li-API, li-intermediates tsa meriana le lisebelisoa tse ling ka lilemo tse fetang leshome. E khona ho fana ka lihlahisoa tse nang le litlamorao tse ikhethang ho fihlela litlhoko tse fetohang tsa bareki.